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What Is A Common Vasomotor Symptom Of Menopause

Insomnia Other Sleep Symptoms Can Be An Early Sign Of Lack Of Estrogen

Dr. Paru David – What are common symptoms of menopause?

If not through hormone therapy, is there a way to treat brain fog or memory issues? Solutions to memory issues might be related to sleep issues or an underlying sleep disorder. It may also be improved by managing stress or treating any underlying mood disorders, such as anxiety or depression, says Faubion.

Nachtigall echoes that sleep is an important issue and often a problem for women during the menopause transition. Many people that I see complain of insomnia, and thats one of the early signs of lack of estrogen that patients in menopause will experience, she says.

Menopause Supplements For Symptom Support

Approximately 50 to 75% of women in the United States have used a natural health product to help alleviate menopausal symptoms. The popularity of natural health product use tends to be the highest among peri- and postmenopausal women. While there are a variety of popular supplements used to help address the symptoms of menopause, more evidence is needed to demonstrate their efficacy, safety, or both.

Black cohosh

Black cohosh is a highly researched herbal supplement used for menopause symptoms. This medicinal herb is believed to have estrogenic effects, however, there is currently a lack of research to support this claim. Research does suggest that it may help to alleviate hot flashes and mood disturbances due to its effect on serotonin receptors. In a randomized controlled trial of 62 menopausal women conducted over a period of three months, black cohosh supplementation resulted in a significant improvement in menopausal symptoms.

Black cohosh is not safe to use for pregnant or lactating women. Potential side effects of using black cohosh can include dizziness, headaches, and mild digestive issues.

St. Johns wort

Chaste tree

Probiotics

Positive benefits have been demonstrated when using oral and vaginal probiotics in the prevention of vaginal infections in post menopausal women, but further research is needed to determine specific effective strains and further support these claims.

Isoflavone Supplements And Extracts

Isoflavones are a group of naturally occurring compounds found in fruits, grains, and vegetables that are structurally similar to estrogen and have an affinity for estrogen receptors. These chemicals have been shown to elicit both estrogen-agonist and estrogen-antagonistic properties when ingested orally in large quantities.4,15 Two specific dietary isoflavones, genistein and daidzein, are found in high concentrations in legumes such as soy, chick peas, lentils, and red clover. Initial interest in these compounds for the management of VMS stemmed from the observation that Asian women, who traditionally consume large quantities of soy in their diet, appear to have lower rates of menopausal symptoms.6,15

Multiple studies have been performed evaluating the efficacy of dietary soy, as well as soy isoflavonoid supplements and extracts, on VMS. Most of these studies were limited by small sample sizes as well as other study design defects, including short study duration and an inability to account for batch-to-batch product variability in the manufacturing of these products. Although some studies reported a slight reduction in symptomatology, most studies failed to demonstrate these products to be more effective than placebo.4,6,9,15

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Your Ears Are Ringing

Or whooshing, or buzzing, or making other sounds only you can hear. Its called tinnitus, and its not clear if this annoying condition is menopause-related, or one of those age-related things that happen to pop up at the same time as menopause.8 Its also a known side effect of medications a lot of us take for other symptoms on this list, including aspirin and Prozac. If you really cant stand it, an audiologist can make you an over-the-ear white noise gadget called a tinnitus masker. If you think more noise will help.

Cardiovascular Issues And Menopause

PPT

Coronary artery disease is the leading cause of morbidity and mortality in men and postmenopausal women. Menopause increases the risk for women still further, independent of age. Before menopause, the risk of CAD for women lags behind the risk for men by approximately 10 years after menopause, it catches up. As a result, mortality from CAD is increasing in women. The Framingham study was pivotal in showing the relation between menopause and increased cardiovascular mortality.

The Womens Health Initiative was a randomized, controlled trial that addressed the issue of whether postmenopausal women should take hormone therapy or estrogen therapy for prevention of CAD more than 27,000 healthy women participated in the trial. The investigators concluded that hormone therapy and estrogen therapy are not indicated for the prevention of CAD.

Emerging analyses of WHI data from the Estrogen-Alone Triala double-blind, placebo-controlled, randomized clinical trial evaluating the effects of conjugated equine estrogens on chronic disease incidence among postmenopausal women with prior hysterectomy and after a mean of 7.1 years of follow-upsuggested that treatment effects differ by age. Compared with older women, younger women receiving CEE had a lower risk of CAD.

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What Conditions Cause Premature Menopause

Your genes, some immune system disorders, or medical procedures can cause premature menopause. Other causes include:

  • Premature ovarian failure. When your ovaries prematurely stop releasing eggs, for unknown reasons, your levels of estrogen and progesterone change. When this happens before youâre 40, it’s called premature ovarian failure. Unlike premature menopause, premature ovarian failure isnât always permanent.

What Happens During Menopause

Natural menopause isnât caused by any type of medical or surgical treatment. Itâs slow and has three stages:

  • Perimenopause. This phase usually begins several years before menopause, when your ovaries slowly make less estrogen. Perimenopause lasts until menopause, the point at which your ovaries stop releasing eggs. In the last 1 to 2 years of this stage, estrogen levels fall faster. Many women have menopause symptoms.
  • Menopause. This is when it’s been a year since you had a period. Your ovaries have stopped releasing eggs and making most of their estrogen.
  • Postmenopause. These are the years after menopause. Menopausal symptoms such as hot flashes usually ease. But health risks related to the loss of estrogen increase as you get older.

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Breast Cancer And Menopause

Estrogen therapy is known to benefit postmenopausal women in a multitude of ways, mostly through the relief of vasomotor symptoms associated with postmenopause. Estrogen is also beneficial for the prevention and treatment of osteoporosis.

Much controversy exists about the use of estrogen and breast cancer. Some studies show an increased risk of breast cancer with postmenopausal estrogen use others show a decrease. A possible link to cancer is also suggested by the finding that breast cancer risk is increased in women with an earlier age at menarche and a later age at menopause. However, a reduction in risk is observed with early age at pregnancy and the interruption of menstrual hormonal changes. The role of estrogen in the development of breast cancer continues to be studied.

In the Womens Health Initiative , the incidence of breast cancer increased in the estrogen-plus-progestin versus placebo arm of the study however, the incidence of breast cancer decreased in the estrogen-only versus placebo arm of the study .

Additional follow-up in patients from the WHI suggested similar results: Breast cancer incidence and mortality were increased in the estrogen-plus-progestin group as compared with the placebo group. The role of combined estrogen-plus-progesterone therapy continues to be puzzling in the development of breast cancer.

Perimenopause: Rocky Road To Menopause

Advances in Our Understanding of the Etiology/Mechanisms of Vasomotor Symptoms

What are the signs of perimenopause? You’re in your 40s, you wake up in a sweat at night, and your periods are erratic and often accompanied by heavy bleeding: Chances are, you’re going through perimenopause. Many women experience an array of symptoms as their hormones shift during the months or years leading up to menopause that is, the natural end of menstruation. Menopause is a point in time, but perimenopause is an extended transitional state. It’s also sometimes referred to as the menopausal transition, although technically, the transition ends 12 months earlier than perimenopause .

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When Does Menopause Begin And How Long Does It Last

Most women first begin developing menopause symptoms about four years before their last period. Symptoms often continue until about four years after a womans last period.

A small number of women experience menopause symptoms for up to a decade before menopause actually occurs, and 1 in 10 women experience menopausal symptoms for 12 years following their last period.

The median age for menopause is 51, though it may occur on average up to two years earlier for Black and Latina women. More studies are needed to understand the onset of menopause for women of color.

There are many factors that help determine when youll begin menopause, including genetics and ovary health. Perimenopause occurs before menopause. Perimenopause is a time when your hormones begin to change in preparation for menopause.

It can last anywhere from a few months to several years. Many women begin perimenopause some point after their mid-40s. Other women skip perimenopause and enter menopause suddenly.

About 1 percent of women begin menopause before the age of 40, which is called premature menopause or primary ovarian insufficiency. About 5 percent of women undergo menopause between the ages of 40 and 45. This is referred to as early menopause.

You Need A New Bra Wardrobe

Are the girls shape-shifting? As estrogen disappears, connective tissue in the breasts becomes dehydrated and loses elasticity. The breast tissue shrinks, loses shape and has trouble defying gravity. At the same time, if youre gaining weight, your breasts are probably sizing up, and so is the circumference of your torso.11

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Treating Underlying Conditions May Help Cognitive Symptoms

The findings of this study point to the fact that not all symptoms related to the menopause transition are hot flashes there are other symptoms, says Stephanie S. Faubion, MD, the director of the Center for Womens Health at the Mayo Clinic in Rochester, Minnesota, and the medical director of the North American Menopause Society .

Included in that are these cognitive type changes that women commonly describe, as well as mood issues that need to be addressed, says Dr. Faubion. That doesnt mean that all these symptoms can be treated with hormone therapy there could be other issues or conditions contributing to these symptoms that need to be addressed and evaluated, she adds.

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Its important to note that we dont know if giving hormone therapy during menopause helps with memory, short or long term. But we do know if youre going to take hormone therapy for other menopause symptoms hot flashes, night sweats it does tend to help with mood, she says. The relationship between depression and memory issues is well-established, adds Faubion.

How Can I Alleviate Menopausal Symptoms

Vasomotor Symptoms Of Menopause

Menopausal symptoms are usually temporary for most women. Hot flashes can be alleviated by dressing in layers of clothing that can easily be removed. Drinking a cold glass of water, or cooling the environment by using an air conditioner or fan, may help relieve these sensations. It is also important to know what triggers these hot flashes, so that they can be avoided. Common triggers include hot foods and drinks, spicy foods, caffeinated beverages, alcohol, stress, and warm weather.

Hot flashes can cause women to wake up during the night, which can lead to insufficient sleep. Caffeine, exercise, and excess alcohol should be avoided before bedtime.

Women who experience vaginal dryness can use OTC water-based vaginal lubricants or moisturizers. Avoid glycerin-containing products, as they can cause burning and irritation.

Relaxation techniques, such as deep breathing, paced breathing, guided imagery, and massage, may relieve symptoms. Smoking cessation may also be beneficial in women experiencing menopause because smoking can cause women to experience menopause earlier and have more hot flashes.

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Hot Flashes During Perimenopause

Most women don’t expect to have hot flashes until , so it can be a big surprise when they show up earlier, during perimenopause. Hot flashes sometimes called hot flushes and given the scientific name of vasomotor symptoms are the most commonly reported symptom of perimenopause. They’re also a regular feature of sudden menopause due to surgery or treatment with certain medications, such as chemotherapy drugs.

Hot flashes tend to come on rapidly and can last from one to five minutes. They range in severity from a fleeting sense of warmth to a feeling of being consumed by fire “from the inside out.” A major hot flash can induce facial and upper-body flushing, sweating, chills, and sometimes confusion. Having one of these at an inconvenient time can be quite disconcerting. Hot flash frequency varies widely. Some women have a few over the course of a week others may experience 10 or more in the daytime, plus some at night.

Most American women have hot flashes around the time of menopause, but studies of other cultures suggest this experience is not universal. Far fewer Japanese, Korean, and Southeast Asian women report having hot flashes. In Mexico’s Yucatan peninsula, women appear not to have any at all. These differences may reflect cultural variations in perceptions, semantics, and lifestyle factors, such as diet.

Keeping Cool And Staying Comfortable

Dress in loose, layered clothing, especially during the nighttime and during warm or unpredictable weather. This can help you manage hot flashes.

Keeping your bedroom cool and avoiding heavy blankets at night can also help reduce your chances of night sweats. If you regularly have night sweats, consider using a waterproof sheet under your bedding to protect your mattress.

You can also carry a portable fan to help cool you down if youre feeling flushed.

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Perimenopause Vs Menopause Vs Postmenopause

During perimenopause, menstrual periods become irregular. Your periods may be late, or you may completely skip one or more periods. Menstrual flow may also become heavier or lighter.

Menopause is defined as a lack of menstruation for one full year.

Postmenopause refers to the years after menopause has occurred.

Reduced Skin Elasticity And Thickness:

Vasomotor Symptoms in Menopause By Dr. Parag Biniwale

Oh no, more wrinkles! Loss of skin moisture, decreased production of natural body oils and collagen are one of the side effects associated with the hormonal fluctuations that you experience during menopause. As a result, youll probably notice that your skin is less elastic and becomes thinner with time.

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Choice Of Progestin Regimen

In the WHI, combined estrogen-progestin therapy was associated with increased risk of CHD and breast cancer, whereas unopposed estrogen was not, suggesting that progestins contribute to both risks. Therefore, there is considerable interest in minimizing progestin dose and duration. Progestins are typically given for 1214 d or daily with continuous regimens. The progestin dose for continuous regimens is typically half of that used for cyclic regimens. Endometrial protection with long-cycle progestins may not be as reliable . A levonorgestrel-containing intrauterine device that releases 20 g of levonorgestrel per day is available for contraceptive use it has also been used off label for endometrial protection in perimenopausal and postmenopausal women using estrogen therapy and appears to prevent endometrial hyperplasia . A lower-dose levonorgestrel-intrauterine device that releases 14 g/d is approved in Europe for postmenopausal hormone therapy. There are theoretical reasons to believe that natural micronized progesterone might be safer for the cardiovascular system , and limited data suggest that it may be associated with a lower breast cancer risk than synthetic progestins , but these potential advantages are not well established.

Urinary And Genital Symptoms

No two vaginas are the same therefore, there is no gold standard for perfect vaginas. However, vaginal health is essential. So, what does a healthy vagina look and feel like? Some discharge is normal, but your vagina shouldnt hurt, or look swollen and inflamed, or feel irritated. Menopause can provoke itching and dryness, however, and this is normal to an extent.

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What Are The Early Signs Of Menopause

Brace yourself, ladies, menopause can be brutal.

There are more symptoms of menopause than these I mentioned, but these are the ones I have experienced. Whatever you do, self-care is so crucial during this time of menopause, so take good care of yourself.

This picture of me taken in 2014 AND 20 lbs heavier than usual, is a game-changer for me. Menopause is brutal! Now, in 2020 Im still having trouble losing the weight. Ive tried intermittent fasting for beginners, going gluten-free, and cutting down on carbs. Nothing seems to help.

Vasomotor Control Of The Umbilicoplacental Circulation

(PDF) Hops for Menopausal Vasomotor Symptoms: Mechanisms ...

The placenta represents an extensive extracorporeal vascular bed that must be perfused by the fetal heart. In addition, for efficient exchange, flow in the maternal and placental circulations must be matched as closely as possible. Hencethere must be local control of vascular resistance within the fetal placental vascular bed. The principal resistance vessels in the placental circulation are the muscular arteries contained within the stem villi. In the absence of any nerves within the placenta,vasomotor control must be performed by local paracrine factors. Nitric oxide, carbon monoxide, and hydrogen sulfide have been identified as having powerful vasodilatory effects. It is thought that under normal conditions, the villous vascular bed is fully dilated and might constrict under hypoxic conditions to redistribute flow to better perfused areas of the placenta, analogous to the situation in the lung.71 Hypoxic inhibition of voltage-gated potassium channels in the smooth muscle cells, leading to calcium influx and contraction, has been implicated as the mechanism.

A. Defresne, V. Bonhomme, in, 2017

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Avasomotor Episodes And Other Brain Dysfunction At The Start Of The Climacteric

Vasomotor episodes , usually referred to as hot flushes or hot flashes, are the most common symptom reported by climacteric women and are the primary cause for seeking medical advice during this period. The rate of reporting of VMEs is not constant throughout the world for example, 50% to 85% of women in North America and Europe report VMEs at the time of cessation of ovarian function. The basis for this discrepancy is not understood, but evolutionary and cultural aspects appear to play important roles . The regular and dose-related diminution of VMEs in symptomatic women described elsewhere in this book attest to the role of estrogen in the occurrence of VMEs.

Thermoregulatory centers in the hypothalamus are largely responsible for the control of vasomotor tone and VMEs . This is discussed in detail elsewhere in this book.

VMEs are only one of many estrogen-dependent signs and symptoms of brain dysfunction that are prominent during the climacteric. Interestingly, these manifestations are generally not conceived as brain symptoms. Rather, they are usually lumped in the category of menopausal symptoms, thereby losing their significance as harbingers of brain dysfunction and perhaps permanent brain disease. This is a massively underdocumented area in need of much research.

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