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What Causes Endometrial Thickening After Menopause

What Can I Do To Help Prevent Endometrial Hyperplasia

What causes Endometrial thickness? – Dr.Smitha Sha

You can take the following steps to reduce the risk of endometrial hyperplasia:

  • If you take estrogen after menopause, you also need to take progestin or progesterone.
  • If your menstrual periods are irregular, birth control pills may be recommended. They contain estrogen along with progestin. Other forms of progestin also may be taken.
  • If you are overweight, losing weight may help. The risk of endometrial cancer increases with the degree of obesity.

Reference:;The American Congress of Obstetricians and Gynecologists.

How To Treat And Prevent Thickened Endometrium

  • In most cases, treat of endometrial hyperplasia involves removal of uterine tissue through dilatation and curettage .
  • Postmenopausal women who are taking replacement hormones causing recurrent endometrial thickening should discuss with their gynecologists options which include either supplementing their therapy with progesterone or stopping therapy.
  • Premenopausal women who have thickened endometrial may take oral contraceptives or progesterone as prescribed to thin out their endometrial lining.
  • Surgical removal of the uterus and other reproductive organs may be advised for some women, particularly those who are postmenopausal or women who are not planning to have children. This will reduce their risk of cancer when their condition does not respond to progesterone therapy.
  • Endometrial thickening can also be treated with oral or injectable progestin. It may also be used as a vaginal creamorin an intrauterine device. However, progestin treatment may cause vaginal bleeding similar to menstrual bleeding.

Q: Why Might A Clinician Need To Measure Endometrial Thickness In Postmenopausal Patients

A: A healthy, postmenopausal woman doesn’t generally need this measured. The whole purpose of measuring the thickness of the endometrium is to check the cause of unexplained bleeding: a thin, distinct endometrium in women with bleeding excludes the possibility of cancer. There are some who believe that if an endometrium measures thick in a non-bleeding patient, intervention is needed, but this is not at all the case.

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What Is Endometrial Hyperplasia

Endometrial hyperplasia is a condition in which the endometrium is abnormally thick. There are four types of endometrial hyperplasia. The types vary by the amount of abnormal cells and the presence of cell changes. These types are: simple endometrial hyperplasia, complex endometrial hyperplasia, simple atypical endometrial hyperplasia, and complex atypical endometrial hyperplasia.

Warm Flashes: The Menopause Classic

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Warm flashes are to menopause what early morning illness is to maternity: the most effective understood as well as often the very first symptom of significant hormonal upheaval. Warm flashes are absolutely nothing more than a feeling of intense heat affecting the face, neck, and breast. It lasts from 30 seconds to 2 mins as well as most often finishes in cold sweats. Three-quarters of females start to suffer from it as early as pre-menopause.Some, the luckiest, have just 1 or 2 warm flashes daily or evening, while others have up to 20 warm flashes per day! And also it lasts: half of the women deal with it for greater than five years and 1 out of 4 for greater than ten years. Endometrial Thickness Of 7Mm After Menopause

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How Is It Diagnosed

To find the cause of your bleeding, the doctor will do a physical exam and review your medical history. You may need one or more of the following tests:

Transvaginal ultrasound: This image helps your doctor check for growths and look at the thickness of your endometrium. Theyâll place a small probe into your vagina. It sends off sound waves to create a picture of the inside of your body.

Endometrial biopsy: The doctor uses a thin tube to take a small sample of the tissue that lines your uterus. Theyâll send it to a lab where scientists will look for anything unusual, like an infection or cancerous cells.

Sonohysterography: Your doctor may use this test to measure the size of a polyp. Theyâll put a saltwater solution inside your uterus to create a clearer ultrasound image.

Hysteroscopy: When the doctor needs to look inside your uterus, theyâll use a hysteroscope. This thin, lighted tube has a camera on one end.

D&C : During this procedure, the doctor opens your cervix. They useÂ;a thin tool to scrape or suck a sample of the uterus lining. They sendÂ;this to a lab that will check for polyps, cancer, or a thickening of the uterine lining .

Ultrasound and biopsy are usually done in your doctorâs office. Hysteroscopy and D&C require anesthesia on one part of or your whole body. Youâll either go to a hospital or an outpatient surgical center.

What Are The Causes Of Endometrial Hyperplasia

Postmenopausal women are at risk for endometrial hyperplasia when undergoing unopposed estrogen replacement therapy. In this type of therapy, progesterone is not administered. Women receiving this type of hormone treatment tend to experience a higher incidence of endometrial hyperplasia.

During a normal menstrual cycle, estrogen causes the endometrium to thicken, preparing the uterus for pregnancy. Then, during ovulation, the ovary releases an egg. Finally, after ovulation, progesterone increases to prepare the endometrium to receive a fertilized egg. When pregnancy does not occur, levels of both estrogen and progesterone decrease and menstruation begins, which sheds the lining of the endometrium.

The endometrial lining fails to shed when there is an absence of progesterone. In these cases, there is a hormonal imbalance where there is too much estrogen and not enough progesterone.

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Causes Of Endometrial Polyps

Polyps are caused by overgrowth of the cells lining the uterus . These cells are very sensitive to the hormone estrogen and grow as a response to circulating levels of estrogen. Endometrial polyps are relatively common in women who :

  • Are menopausal or postmenopausal
  • Are adolescents: Although this is less common
  • Are obese
  • Have Lynch syndrome: Women who have Lynch syndrome increased incidences of endometrial polyps compared to the general population, and also have an increased risk of endometrial cancer.
  • Use Tamoxifen: This is a drug therapy for breast cancer that places women at a higher risk for developing endometrial polyps and sometimes cancer.

Strengths And Limitations Of The Study

What Causes Endometrial Cancer And What Are The Symptoms?
  • Most of the available studies focus on endometrial changes in postmenopausal women, whereas in this study thorough ultrasound assessment of genital organs has been done by calculating uterine and ovarian volume, in addition to determination of ET and correlation has been established

  • Though in general, the total number of patients required to conduct the study far exceeded the required minimum sample size, there were less number of patients in some of the subcategories, for example; cancer breast patients receiving tamoxifen therapy

  • When ET was more than 4 mm , only 16 accepted and had endometrial sampling. If all of them had agreed for the procedure, it would have sizably improved the strength of histopathological findings, so as to frame a guideline for management of asymptomatic postmenopausal endometrial thickening.

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Causes Of Postmenopausal Bleeding

There can be several causes of postmenopausal bleeding.

The most common causes are:

  • inflammation and thinning of the vaginal lining or womb lining caused by lower oestrogen levels
  • cervical or womb polyps growths that are usually non-cancerous
  • a thickened womb lining this can be caused by hormone replacement therapy , high levels of oestrogen or being overweight, and can lead to womb cancer

Less commonly, postmenopausal bleeding is caused by cancer, such as ovarian and womb cancer.

Symptoms Of Endometriosis After Menopause

The list of endometriosis symptoms after menopause can include the following:;

  • Pelvic pain
  • Gastrointestinal problems;
  • Pain during sexual intercourse

Postmenopausal women should keep in mind that they are also at higher risk of autoimmune disorders – like allergies, asthma, and fibromyalgia – as well as other health conditions, such as chronic fatigue syndrome and hypothyroidism, among others.

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What Questions Should I Ask My Doctor

If you have endometrial hyperplasia, you may want to ask your healthcare provider:

  • Why did I get endometrial hyperplasia?
  • What type of endometrial hyperplasia do I have?
  • Am I at increased risk for endometrial or uterine cancer? If so, how can I lower that risk?
  • If Im overweight, can I be referred to a weight management consultant?
  • What is the best treatment for the type of endometrial hyperplasia I have?
  • What are the treatment risks and side effects?
  • Are my family members at risk for developing endometrial hyperplasia? If so, what can they do to lower that risk?
  • What type of follow-up care do I need after treatment?
  • Should I look out for signs of complications?

A note from Cleveland Clinic

Endometrial hyperplasia is a condition that causes abnormal uterine bleeding. These symptoms can be uncomfortable and disruptive. Many women find relief through progestin hormone treatments. Women who have atypical endometrial hyperplasia have a higher risk of developing uterine cancer. A hysterectomy stops symptoms and eliminates cancer risk. Talk to your healthcare provider about the best treatment for you.

Last reviewed by a Cleveland Clinic medical professional on 08/28/2020.

References

What To Do Versus Warm Flashes

Obs&Gyn: Postmenopausal bleeding

In more than 85% of cases, hormonal agent substitute treatment can eliminate the worst hot flashes within a few weeks. As for non-hormonal therapies, such as herbal medicine , can in some cases relieve them, however less effectively and with less uniformity than HRT. Endometrial Thickness Of 7Mm After Menopause

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Treatment Options And Prevention For Endometrial Polyp

Treatment for endometrial polyps involves decreasing circulating levels of estrogen to help stop their growth or removal of the polyps altogether. Your physician may recommend the following watchful waiting, medication, or surgical removal.

  • Watchful waiting: Small polyps that are asymptomatic might get better on their own. Treatment of these small polyps that you may not even know are there is unnecessary unless you have a greater risk of endometrial cancer.
  • Medication: Certain hormonal medications, including progestins and gonadotropin-releasing hormone agonists, may lessen symptoms of the polyp. But taking such medications is usually a short-term solution at best symptoms typically recur once you stop taking the medicine.
  • Surgical removal: During hysteroscopy, instruments inserted through the hysteroscope the device your physician uses to see inside your uterus make it possible to remove polyps. The removed polyp will likely be sent to a lab for microscopic examination.

Why Is Hysterectomy Performed

A hysterectomy may be performed to treat:

  • Abnormal vaginal bleeding that is not controlled by other treatment methods.
  • Severe endometriosis .
  • Leiomyomas or uterine fibroids that have increased in size, are painful or are causing bleeding.
  • Increased pelvic pain related to the uterus but not controlled by other treatment.
  • Uterine prolapse that can lead to urinary incontinence or difficulty with bowel movements.
  • Cervical or uterine cancer or abnormalities that may lead to cancer for cancer prevention.

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Conquering Presumptions Concerning Menopause

The technique of this significant inner upheaval is often worrying. Right here is some info to establish the document straight.

The earlier you have your duration, the earlier you undergo menopauseWrong. There is no web link between the age of very first menstrual cycle as well as the age at which it quits. Nor exists a web link between the age of menopause and the age of taking the birth control pill . Menopause takes place when the supply of eggs, built up before birth, is practically worn down. However out of the initial stock of numerous million roots, just 500 are released during ovulation throughout life. The rest, 99.9% of the ovarian reserve, dies normally by apoptosis, or programmed cell death. Endometrial Thickness Of 7Mm After Menopause

The average age of menopause does not transform regardless of the aging of the population.Real. The average age of menopause is 51, an age that does not vary. When menopause takes place prior to the age of 40, it is called early ovarian failure. It is after that required to search for a possible genetic cause linked to an X chromosome problem. It is important to compensate for the hormone shortage in estrogens by taking hormonal agent replacement therapy until the ordinary age of menopause. Or else, the threat of death from cardiovascular disease is much more significant. Endometrial Thickness Of 7Mm After Menopause

Having Had Children Decreases Your Risk

Causes of Endometrial Thickeness Hyperplasia in Women After Menopause Postmenopausal Treatment

Studies show having children lowers womb cancer risk by around a third. The risk decreases with the more children a women has.;

Oestrogen levels are low and progesterone levels are high during pregnancy. During the menstrual cycle, there is oestrogen in the body without progesterone. This is called unopposed oestrogen.;

Unopposed oestrogen increases womb cancer risk. So anything that stops this lowers the risk of womb cancer.;

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How Is Pelvic Pain Treated

The treatment of pelvic pain varies by what the cause is, how intense the pain is, and how often the pain occurs. Sometimes pelvic pain is treated with medicines, including antibiotics, if necessary. If the pain results from a problem with one of the pelvic organs, the treatment might involve surgery or other procedures. Physical therapy can be helpful in some cases. Also, because living with chronic pelvic pain can be stressful and upsetting, studies have shown benefit to working with a trained counselor, psychologist, or psychiatrist in many cases. A doctor can provide more information about various treatments for pelvic pain.

Last reviewed by a Cleveland Clinic medical professional on 12/05/2014.

References

How To Detect Fibroids After Menopause Symptoms And Methods Of Diagnosis

The medical literature describes many symptoms of fibroids after menopause, but, most often they are talking about three of them:

  • Increased profuse menstrual bleeding.;
  • Large fibroids can put pressure on the bladder or rectum, leading to impaired urination, problems with stool.;
  • Stomach enlargement. Many women ignore this symptom because they believe that they just gained weight.;

Other possible manifestations: pain in the lower abdomen, lower back, legs, pain during intercourse. Although you need to remember that these signs are nonspecific and can often indicate other diseases

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Can We Lower Our Cardiovascular Risk

Yes, by preserving a healthy way of living, dealing with against cigarette smoking and overweight, exercising regular physical exercise, as well as very closely monitoring blood pressure, the look of possible diabetes, and also cholesterol degrees.Lets not fail to remember that cardiovascular diseases are the leading cause of death among ladies.

Causes Of Uterine Fibroids Appearance

8mm Endometrial Thickness Postmenopausal Treatment ...

Currently, scientists are forced to admit defeat the causes of myomatous nodes are unknown. There are two main theories, but none of them has strong evidence:

  • Embryonic theory suggests that abnormalities occur during fetal development. The smooth muscle cells of the uterus of the embryo do not finish their development for a long time, until the 38th week of pregnancy, and are in an unstable state , due to which there is a higher risk occurrence of defects in them.
  • Based on the traumatic theory, a defect in the cells of the myometrium occurs due to repeatedly repeated menstrual cycles, inflammatory processes, abortions, curettage of the uterus, the inaccurate performance of obstetric manual methods during childbirth, and a small number of pregnancies.

The uterine fibroids after menopause nods always arise from a single cell. Due to damage, this cell begins to divide and forms a node.

Uterine fibroids are a disease that no woman is safe. Since the causes of the occurrence are unknown, effective methods of prevention do not exist, except for regular visits to the gynecologist twice a year. The doctor may pay attention to nonspecific signs and schedule an examination.

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Q: What Other Providers Or Treatment Options Might A Patient Need To Seek Out After This Exam

A: When it comes to postmenopausal endometrial thickness, in an average-risk woman with postmenopausal bleeding, a thin, distinct echo of less than 4 mm would require no further intervention, nor would an endometrial echo of less than 3 mm in virtually any other woman.

If an endometrial echo cannot be adequately visualized secondary to coexisting fibroids, adenomyosis, axial uterus, previous surgery or marked obesity, then the next step is often saline infusionsonohysterography to better delineate the endometrial contents and distinguish global from focal pathology. This is because global pathology may allow for a blind biopsy, whereas focal pathology should be biopsied under direct visualization with a hysteroscopic procedure.

Saline infusion sonogram demonstrating polyp

What Are The Benefits Of An Endometrial Biopsy

An endometrial biopsy is the most common and accurate test used to diagnose endometrial cancer. The lab should have the results in about a week. Your physician will share the results with you and go over a treatment plan depending on the results.

Last reviewed by a Cleveland Clinic medical professional on 01/04/2021.

References

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How Is Polycystic Ovary Syndrome Treated

Although PCOS can be treated with medications, treatment is often highly dependent on your goals and your symptoms.

If you want to become pregnant, you may need the assistance of oral or injected fertility medications. If you do not want to become pregnant, you may consider birth control pills to prevent pregnancy and regulate periods. Periods can also be regulated using the hormone progesterone.

There is also a non-hormonal treatment option, which is a medication usually used for diabetes. Even if you don’t have diabetes, this medication may help restore fertility and assist with weight loss.

Other symptoms such as unwanted hair growth, acne, obesity, and diabetes should be managed by specialists in those areas. Birth control pills are often helpful in the treatment of hair growth and acne.

You should discuss specific treatment options with your physician.

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