Pregnant Women Over 50 ‘do Pretty Well’ Study Finds
03 February 2012
The average age of women becoming mothers has risen in the United States, and in the last 20 years, a few women have even entered motherhood in their 60s.
A new study of 101 women age 50 and older who had children using donated eggs reveals that pregnancy at this age carries about the same risks as similarly induced pregnancies in younger women. The study is the largest one to date looking at pregnancy in post-menopausal women.
“These women do really pretty well,” said Dr. Mark Sauer, senior author of the article and chief of the division of reproductive endocrinology and infertility at Columbia University Medical Center, where all the women in the study received IVF.
“If they’re well-screened and well cared for, they really should do O.K.,” Sauer said.
The study found women over age 50 had similar rates of complications, such as gestational diabetes and preterm labor, as women under age 42 who became pregnant after receiving donated eggs.
And although the older women had slightly higher rates of high blood pressure, that difference was small, and may have been due to chance.
The study is published in the February issue of the American Journal of Perinatology.
Pregnancy at older ages
While Sauer said the results of the study were surprising in terms of how well older mothers did, he noted that the women were highly screened and highly motivated.
“The uterus is a very different organ than the ovaries,” Sauer said.
Eggs, however, are a different story.
Can You Get Pregnant After Menopause
Females are born with millions of eggs inside their ovaries. Until puberty, these eggs remain in a state of latency; however, after reaching puberty, drastic changes occur in the biochemical environment of the body due to hormones. As a result of hormonal fluctuations, every month, few eggs are released from the ovary but only one egg achieves complete maturation. Once this egg is ovulated, it is released into the fallopian tubules to allow fertilization of egg and a normal pregnancy .
With the passage of time, the release of mature eggs from ovaries become less frequent and the women become less capable of producing fully matured eggs. Needless to say that less frequent production of mature eggs is partly due to physiological aging and partly due to hormonal changes, which ultimately leads to menopause. In short, it;marks the end of female fertility.
Why Does Ivf With Donor Eggs Fail
Very often it is not clear why the embryos do not develop in the womb properly but it could be caused by one of these reasons: It could be chromosomes problems many healthy-looking embryos have defective chromosomes. This, in turn, may cause IVF failure. It could be because of the poor blood flow to the womb.
Recommended Reading: Is Dizziness A Symptom Of Menopause
Egg Donor Cyprus: Screening And Selection
Egg donors must be screened before they are allowed to take part in our egg donation program. The egg donor screening process includes medical, fertility and genetic examination. Once the candidate has completed the screening process, her profile will be uploaded into our database that is only viewable by patients who are in search of an egg donor.
The selection is usually done based on the physical characteristics, nationality and/or interests of the egg donor. For this reason, intended parents will be required to fill out a medical form to provide your photo or a list of physical attributes you desire in an egg donor. Depending on your criteria, you will be offered 3 to 5 egg donor profiles to help you choose the right one. After you select your egg donor, egg donation in Cyprus can begin.
How To Detect Fibroids After Menopause Symptoms And Methods Of Diagnosis
The medical literature describes many symptoms of fibroids after menopause, but, most often they are talking about three of them:
- Increased profuse menstrual bleeding.;
- Large fibroids can put pressure on the bladder or rectum, leading to impaired urination, problems with stool.;
- Stomach enlargement. Many women ignore this symptom because they believe that they just gained weight.;
Other possible manifestations: pain in the lower abdomen, lower back, legs, pain during intercourse. Although you need to remember that these signs are nonspecific and can often indicate other diseases
Don’t Miss: Is Dizziness A Symptom Of Menopause
Do I Need To See A Gynecologist After Menopause
As you age, youll notice several changes, beginning with reduced periods. This is something you should look out for after the age of 40. This is generally when female hormones begin changing, which results in several uncomfortable symptoms, including hot flashes, which usually appear during perimenopause. If you have gone a year without a menstrual period, you have likely reached the menopausal phase.;
Your body will continue to change after menopause, and many women experience symptoms that require gynecological care. For example, if you experience irritation of the vagina and vulva, sexual intercourse may become painful. Some women experience pelvic organ prolapse when the muscles that support their bladder, rectum, and uterus become significantly weaker. You may also experience urinary incontinence, which requires care as well. At the end of the day, maintaining a solid relationship with your gynecologist can help you keep good health after menopause.;
So, when youre asking yourself, do I need to see a gynecologist after menopause? the answer is yes. You must know the available answers when you search gynecologist for seniors near me. However, so long as your exams have been healthy in the preceding years, you will not have to visit your doctor as often as you did pre-menopause.;
Potential Risks Of Pregnancy During Perimenopause
While there are always some risks involved in pregnancy, the risks are much higher during perimenopause. There is potential for a variety of complications and women who are pregnant during perimenopause are considered to be high-risk and should be monitored more closely by medical professionals.;
Its important to know that women over the age of 40 have about a 50% chance of miscarriage. If you are a woman in your perimenopausal years and you are contemplating pregnancy, its highly recommended that you talk with your doctor to make sure you are well informed and medically cleared of any preexisting conditions that could complicate pregnancy even more.;
Health risks during pregnancy that increase after the age of 35 can include:
- Premature or low birth weight
Don’t Miss: Intrarosa Pros And Cons
Can Women Conceive After Menopause
Yes. With the help of IVF, women who have gone through menopause can still get pregnant, whether menopause came early or at a more expected time. You will need to use donor eggs, but chances are that you can still carry and deliver a healthy baby. A study;carried out at the Columbia University Medical center and published in The American Journal of Perinatology followed 101 women over the age of 50 who underwent IVF with donor eggs and found that the outcomes for both mothers and babies were as good for the post-menopausal women as they were for women under the age of 42.
If you think that you may be undergoing menopause early and are hoping to have a baby, it is a good idea to get professional advice as soon as possible. Your fertility team can run a series of tests to find out whether you are in fact going through menopause, and which treatment options make sense for your situation. If you decide to try IVF with donor eggs, you can use eggs from a known donor or go with a donor from an egg donation program, where you can choose to know the identity of the donor or proceed anonymously.
Egg Donation In Cyprus
Egg donation in Cyprus is anonymous. Anonymous egg donation uses eggs donated by previously screened egg donors whose identity is not revealed.
At EuroCARE IVF, we take great care to maintain anonymity of both the donor and the recipient . Both parties may remain anonymous with each agreeing not to seek information about the other.
Potential egg donors must be between the ages of 20 and 28. All candidates are screened according to our guidelines before being accepted and added to our database. The various tests, including a physical exam, laboratory and genetic testing, assure good medical health and an absence of genetic diseases that could be passed onto the child.
Read Also: Dizziness During Menopause
Can A Woman Get Pregnant After Menopause
Once youve reached menopause, a womans hormone levels are no longer the same. LH and FSH levels remain high and estrogen and progesterone levels remain low. After menopause, you will no longer ovulate and your ability to get pregnant with your own eggs becomes limited.
Although the number and quality of your eggs inevitably declines after menopause, there are still ways you can benefit from IVF in Cyprus. EuroCARE IVF patients have the ability to use frozen eggs or donor eggs from our egg donor database.
In addition to egg donation, patients may consider Tandem IVF. This is a special type of IVF in Cyprus that allows you to use your own eggs along with eggs provided by an egg donor as a back-up plan. Embryo donation is also an option if you are trying to conceive after menopause. Our fertility specialists are available to discuss treatment options based on your personal circumstances.
How Much Does Ivf With Egg Donor Cost
Our current cost for a complete egg donation cycle is $27,000. This includes the donor’s fee of $7,000 to $9,000 and $400 for short term medical insurance for the donor. The cost of donor egg IVF varies greatly at different IVF centers. Some clinics charge over $30,000 without medications for a single donor cycle.
Read Also: Is Dizziness A Symptom Of Menopause
Women After 50 Can Have Safe Pregnancy
But They Have More C-sections, Diabetes, High Blood Pressure
Nov. 12, 2002 — As the years pass and technology improves, the barrier to pregnancy gets pushed farther and farther back. It used to be thought that women shouldn’t get pregnant over the age of 40. Today, 50-something women and their doctors wonder if it is safe to push that barrier even farther.
“There is no medical reason” not to, said Richard J. Paulson, MD, in a news conference today. Chief of the division of reproductive endocrinology and fertility at the University of Southern California Keck School of Medicine, he is also the lead investigator on a study that appears in the Nov. 13 issue of The Journal of the American Medical Association.
The study of women aged 50 to 63, all of whom were postmenopausal, revealed an increased number of complications, but nothing that cannot be handled by close monitoring and quality healthcare.
After menopause, a woman no longer produces eggs and thus cannot become pregnant naturally. But although eggs succumb to this biological clock, pregnancy is still possible using a donor egg. Therefore, all of the women in the study had an egg from a younger woman implanted into her uterus.
“There are really two biological clocks: One for the ovary, which seems to run out, and one for the rest of the reproductive system, which seems to go on,” said Paulson. All that’s needed is a little priming with the hormones estrogen and progesterone, followed by a donated, fertilized egg.
How To Increase Your Chances Of Getting Pregnant After 40
Before we dive into specific actions that can be taken to improve the odds of getting pregnant after 40, its important we set the stage properly.; Females are born with all the eggs they will ever have. For most of a females life, these eggs simply sit in a waiting pool in an immature stage until it is their turn to be recruited and developed with the chance of being ovulated.;
For a long while, it was assumed that these eggs in the waiting pool degrade as a woman aged.;; By the time a woman reached 40, these eggs had been slowly withering away for 40+ years and substantially degraded. So, when they were recruited out of their waiting pool they were destined for failure.; However, reproductive endocrinologists now believe eggs remain in excellent condition as long as they remain in the waiting pool.
On the other hand, a womans hormonal and thus ovarian environment indeed deteriorate quite noticeably as a woman ages. This environment and the hormones inside the ovary are critical for proper egg development. If a healthy immature egg is recruited into this poor ovarian environment it is unable to develop properly. They end up being poor quality by the time ovulation occurs because they enter a poor ovarian environment for development.
This suggests the following formula: Fix the ovarian environment -> fix egg quality -> improve reproductive outcomes. So, what can you do to fix the ovarian environment. Here we will cover three easy changes you can make to your life.
Also Check: Is Dizziness A Symptom Of Menopause
What Is The Difference Between Egg Donation And Ivf
Broadly speaking, by in vitro fertilization we mean the process of fusing artificially the eggs and the sperms of the intended parents, with the purpose of creating new embryos and achieve a pregnancy after transferring them to the patient’s uterus.
On the other hand, egg donation is a procedure that is part of the IVF process when the patient’s own eggs are unable to be used. In these cases, donor eggs are fertilized exactly as explained in the previous paragraph. To sum up, egg donation is all about receiving donated eggs in order for the patient to get pregnant through IVF.
There Are Several Potential Causes But Some Are More Serious Than Others
In most cases, postmenopausal bleeding is caused by issues such as endometrial atrophy , vaginal atrophy, fibroids, or endometrial polyps. The bleeding could also be a sign of endometrial cancera malignancy of the uterine lining, but only in a small number of cases. A 2018 study by the National Cancer Institute found that only about 9 percent of postmenopausal women who saw a doctor for bleeding later received a diagnosis of endometrial cancer.
Still, we want the option to intervene early if it is cancer, since treating it sooner leads to better outcomes, Mantia-Smaldone said.
If endometrial cancer is found early, a woman has a 95 percent chance of surviving the cancer for at least 5 years.
Read Also: Is Lightheadedness A Symptom Of Menopause
Pregnancy Considerations After Donor Egg Ivf
The protocol for IVF with donor eggs is very similar to that of a frozen embryo transfer. The intended mother is prescribed exogenous estrogen , which both stimulates endometrial growth and simultaneously suppresses her natural cycle of folliculogenesis and ovulation. Having a normal menstrual cycle is not a prerequisite, however, because even in menopause the endometrium will grow in response to estrogen. Once a sufficient endometrial thickness is confirmed by transvaginal ultrasound , the woman is instructed to start transvaginal progesterone; this simulates a luteal phase and prepares the endometrium for implantation. Simultaneously, the donor eggs are carefully thawed in the embryology laboratory, and each is injected with a single sperm from the intended father. Therefore, a future genetic test would show that the child is biologically related to the father but not to the birth mother. Embryo transfer occurs after 5 days of development, at the blastocyst stage, when the embryo is almost ready to hatch and adhere to the appropriately synchronized endometrium. If a pregnancy results, it is essential that the woman remain on progesterone because the placenta does not start to produce it until 7 weeks gestation or later.
Should You Use An Egg Donor
If we compare the disappointing pregnancy rates for women in their 40s who use their own eggs to success rates using egg donation, we see the latter group having a much higher success rate nationally nearly a 50% live birth rate.
The decision to use an egg donor is a significant emotional challenge. The choice is made even more confusing given the media display of celebrities in their late 40s and early 50s not disclosing, but presumably, having used an egg donor. This lack of transparency only heightens your stress and creates unrealistic expectations when you are faced with DOR.
Read Also: Menopause Dizzy Spells
Is My Body Fit Enough To Carry A Child
These days, a woman in her fifties is often in as good or even better shape than women fifteen or even twenty years her junior. But regardless of age, it is always recommended for the potential mother to bring her body to its absolute peak of wellness before beginning treatment that could lead to a pregnancy.
While we dont suggest it, the current world record for the;oldest woman to give birth as a result of IVF is 72. One should consider the implications of having a baby at any age and ensure there is a strong support system for the child into adulthood should anything happen to the mother.
Selecting A Donor Is Time
It requires perseverance and patience to select a donor. In the profile of egg donors, a lot of things like eye color, hair color, height, weight, skin color, ethnicity, educational level, religion, and other details are mentioned. The couple has to screen through the profile and select the one closest to their preferences.
You May Like: How Long Between Periods During Menopause
Pregnancy After Menopause: Fantasy Yes Crazy No We Can Make It Happen
Pregnancy After Menopause: Fantasy Yes, Crazy No, We Can Make it Happen
Ronny Cammareri: why didnt you wait for the right man?;Loretta Castorini: He didnt come!Ronny Cammareri: Im here!;Loretta Castorini: Youre late!
So the love of your life came too late and your last period came too early. Pregnancy,then,must be out of the question? Not so. With the use of donor egg IVF your fantasy of family can be realized.
Heres how it works: The intended mother,or recipient, is matched with a young ,healthy egg donor whose physical characteristics and cultural background are similar to her own. Most egg donations are anonymous but designated donation between known parties can also be executed. Both donor and recipient are prescribed regimens of hormonal treatments: the donors to develop multiple eggs , the recipients to prepare her endometrium, or uterine lining, to receive embryos created from the fertilization of the donated eggs with her partners sperm. The embryos,once created, are cultured and grown for five days. The goal is to have two well expanded blastocyst-staged embryos to transfer to the uterus of the intended mother. Supernumary embryos of equal quality may be cryopreserved for future attempts to create or expand a family.